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Introduction

Hydromorphone is a potent Opioid medication that includes an active ingredient such as Morphine. This medication has an analgesic potency that is two to eight times greater than that of Morphine.

This medically is commonly used to treat and manage moderate to severe acute and severe chronic pain that requires opioid analgesics when non-opioid and other Opioid medications are not sufficient.

It is recommended that this medication be used only on a doctor’s prescription for short-term treatment to manage pain and alleviate discomfort. Its rapid onset of action makes it more effective in relieving and managing pain.

Hydromorphone is the most powerful Opioid medicine, and because of that, it contains a higher risk of abuse, misuse, and addiction. Using any other opioid medication with this medication can lead to serious drug interaction that may prove to be fatal to your health.

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Why Hydromorphone Is Used?

  • Moderate pain: Hydromorphone helps treat severe pain that causes a level of discomfort and distracts and interferes with daily activities.
  • Severe acute pain: It also treats sudden, intense pain that can be disabling and makes it hard for a person to do anything.
  • Severe chronic pain: Being a potent pain reliever, hydromorphone is also used to treat severe chronic pain that lasts for a longer period of time, causing high-intensity pain that interferes with a person’s daily life that disturbs social, work life, and overall quality of life.

These medications come in immediate-release and extended-release tablets that will be prescribed to you by your doctor according to your health needs and based on the intensity of pain.

Hydromorphone extended-release capsules or extended-release tablets are prescribed for opioid-tolerant patients only. If you are uncertain whether you are opioid-tolerant or not, then talk to your doctor before using this medicine.

How It Works?

This medication works by changing the way how your brain and nerves respond to pain. Hydromorphone directly works on the Opioid receptors of the brain. It helps in reducing the feeling of pain by interrupting the way the nerves signal the pain between the brain and the body.

Being a potent Opioid medication that is 5 – 10 times stronger than Morphine, Hydromorphone crosses the blood-brain barrier faster, resulting in quicker onset and peak of analgesic activity, causing sedation and relaxation.

Who Cannot Take Hydromorphone?

Most adults and children suffering from severe acute or chronic pain can use this medication on prescription for effective pain relief. However, it is not considered safe to use this medication even on a doctor’s prescription.

You must avoid using Hydromorphone if you have any of these conditions such as –

  • Patients with gastrointestinal obstruction
  • Have a history of kidney or liver disease
  • Women who are pregnant, trying for pregnancy, or breastfeeding mothers
  • Severe lung disease or breathing problems
  • Older adults over 65 years of age
  • Suffering from mental health issues
  • Already using any opioid medication

Side Effects of Hydromorphone

Hydromorphone causes certain common to serious side effects that sometimes can be life-threatening to a person, especially when not used as prescribed by a doctor or a healthcare provider.

Common Side Effects

  • Headache
  • Diarrhea
  • Stomach pain
  • Constipation
  • Vomiting
  • Dry mouth
  • Sweating
  • Fatigue
  • Euphoria
  • Redness on the skin

Serious Side Effects

  • Hypotension: Causing symptoms like weakness and unusual tiredness.
  • Trouble breathing: It can affect your respiratory system and can slow, shallow, or stop your breathing, leading to coma or death.
  • Drug dependence: Regularly using this medication for an extended period can develop a dependency that leads to addiction over time.
  • Loss of appetite: It can lead to weight loss by causing stomach problems and frequent constipation.
  • Difficulty in swallowing: You may experience difficulty in swallowing food.
  • Insomnia: causing symptoms like difficulty in sleep initiation and inability to stay asleep for a longer period of time.
  • Liver failure: Prolonged use of Hydromorphone (a pain medicine) can directly affect your liver, leading to severe liver damage.
  • Allergic reactions: In some rare cases, you may experience severe allergic reactions like itching, rashes, hives, and swelling on face, tongue, lips, or throat.

How To Use Hydromorphone Safely?

Hydromorphone has a higher risk of abuse and misuse, and it can cause certain serious side effects that can be life-threatening. To safely use this medication, you must avoid making these mistakes while using this medication.

  • Avoid using alcohol or any other substance, such as (drugs or heroin) to prevent any severe withdrawal symptoms.
  • Any severe allergic reaction to this medication is rarely seen, but in some rare cases, it may cause certain allergic reactions like itching, rashes, swelling, or hives, and if you experience any of these, stop using the medication immediately.
  • It is strictly advised not to use Hydromorphone during pregnancy or nursing period, as the formula may pass to the baby through milk.
  • You must tell your doctor if you have been suffering from multiple health conditions or if you have any other mental disorder to prevent any adverse effects of this medication.
  • Include dietary fiber in your meals, and stay hydrated throughout the day to prevent constipation.

Final Words

Hydromorphone is recommended to be used for short-term treatment of pain, as it can cause dependency on this medication that can lead to addiction when used on a regular basis for a prolonged period of time.

Being a potent opioid medication, hydromorphone contains a higher risk of abuse and misuse. You must avoid sharing this medication with others, especially children and older adults, as they have weaker metabolisms than younger adults.

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